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They are opposed, and the results are often disappointing. A hyperintensity or T2 hyperintensity is an area of high intensity on types of magnetic resonance imaging (MRI) scans of the brain of a human or of another mammal that reflect lesions produced largely by demyelination and axonal loss. Bethesda, MD 20894, Web Policies Dr. A, I recently had an MRI and the radiologist reading is as follows: Some minimal T2 signal abnormality is noted in the periventricular white matter of the atria of the lateral ventricle, right greater than left. Is there mild heterogeneous T2 signal change within the supraspinatus? it goes on to say otherwise unremarkable. Radiologists play a valuable role in helping narrow the differential diagnosis by integrating patient history and laboratory test results with key imaging characteristics. but no futher study has taken place. Ma YJ, Shao H, Fan S, Lu X, Du J, Young IR, Bydder GM. Neuroimaging Clin N Am. These cookies ensure basic functionalities and security features of the website, anonymously. I am really worried? Reference article, Radiopaedia.org (Accessed on 05 Mar 2023) https://doi.org/10.53347/rID-16494, View Patrick J Rock's current disclosures, see full revision history and disclosures, dependence of magnetization (proton density, field strength and temperature), effect of gradient strength and bandwidth on slice thickness, longitudinal and transverse magnetization, molecular tumbling rate effects on T1 and T2. The meaning of PROLONG is to lengthen in time : continue. ADVERTISEMENT: Supporters see fewer/no ads. What does this mean There are a few scattered small foci of t2 hyperintensity in the periventricular and subcortical white matter of each cerbral white matter of each cerebral hemishere. The pattern of T1 lesions with contrast changes from month to month. 2020 Jul;16(3):369-375. doi: 10.3988/jcn.2020.16.3.369. One of the major challenges associated with the T2 assessment according to the RANO criteria is the differentiation between T2-progress and other causes of T2 signal increase, such as edema, radiation effects, decreased corticosteroid dosing, seizures, postoperative changes, or even ischemic injury. CCF-Neuro-M.D.-PW. This is often due to a combination of atherosclerosis, demyelination (loss of the "white matter" covering the nerves ), and scarring. The magnitude of the MR signal after an RF-pulse is in turn, dependent on two factors: T1 reflects the length of time it takes for regrowth of. - Apr 12, 2014. The spots (called lesions) on the scan are areas of active inflammation. Studies suggest that a combination of MTA and severe WMH showed more than a fourfold increase in the frequency of mild cognitive deficits. MeSH i'm 43 and started having migraine with aura at 41. Please help keep this site free for everyone in the world! Carroll T, Smith CD, Liu X, Bonaventura B, Mann N, Liu J, Ebraheim NA. What does it mean? 5 What is the grading scale for supraspinatus tendinopathy? This finding has been variously attributed to the presence of fat, muscle, connective tissue, abnormal vascularity, or degenerative changes. Intramedullary cord hyperintensity at T2-weighted MRI is a common imaging feature of disease in the spinal cord, but it is nonspecific. There are innumerable punctate T2/FLARE hyperintense lesions throughout the subcortical and periventricular white matter. It says: It does not store any personal data. WMH's are also referred to as Leukoaraiosis and are often found in CT or MRI's of older patients. Get prescriptions or refills through a video chat, if the doctor feels the prescriptions are medically appropriate. What is the grading scale for supraspinatus tendinopathy? and transmitted securely. The dipole-dipole interaction is also increased the strength of the local field which is dependent on the proximity of the adjacent dipoles. Which following agency provides standards for indoor air quality? A T2WI relies upon the transverse relaxation (also known as "spin-spin" relaxation) of the net magnetization vector (NMV). HealthTap uses cookies to enhance your site experience and for analytics and advertising purposes. Video chat with a U.S. board-certified doctor 24/7 in a minute. For these, please consult a doctor (virtually or in person). The .gov means its official. Careers. Objective: Increased signal intensity within the distal portion of the supraspinatus tendon during MR imaging is a frequent observation even in healthy subjects. The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. J Med Imaging Radiat Oncol. FOIA Treatments such as Prolozone Therapy can significantly speed up the healing process. It also found the following: There is a focus of uniform T2 prolongation in the medial lower pole of the right kidney measuring 20 mm in diameter. . Example Sentences. For potential or actual medical emergencies, immediately call 911 or your local emergency service. An official website of the United States government. HHS Vulnerability Disclosure, Help You have brain structures that show up white on, in this area. after doing so it was noted on the report that a t2 hyperintensity had been observed on my left kidney . what does it mean? Educational text answers on HealthTap are not intended for individual diagnosis, treatment or prescription. These small regions of high intensity are observed on T2 weighted MRI images (typically created using 3D FLAIR) within cerebral white matter (white matter . This cookie is set by GDPR Cookie Consent plugin. In spin echo sequences, immediately after the 90 pulse, all the spinning dipoles within the slice are exactly in phase. Cervical (neck) spinal cord T2/FLAIR lesions could cause tingling and numbness in the hands and legs. Never disregard or delay professional medical advice in person because of anything on HealthTap. My doctor wants me to have blood drawn, a urinalysis and an ultrasound. Causes including simple MR artefacts, trauma, primary and secondary tumours, radiation myelitis and diastematomyelia were discussed in Part A. My 12yr old has a growing brain tumor - Neurology Community. I had a lumbar MRI due to increased pain and found a lot of degenerative changes. Synonym Discussion of Prolong. FInstP PJAOBEPFIPSM, CSci JWMFIPEM. These cookies track visitors across websites and collect information to provide customized ads. What is increased T2 signal on MRI report? Several treatments can prevent 80% of new T2 lesions from developing in the brain. The rapid motion results in the T1 and T2 being about the same in pure water. Out of these, the cookies that are categorized as necessary are stored on your browser as they are essential for the working of basic functionalities of the website. Please note, we cannot prescribe controlled substances, diet pills, antipsychotics, or other abusable medications. Punctate focus of t2 prolongation in the left centrum semiovale, What does it mean there is focal abnormal t2 and t1 prolongation. On this Wikipedia the language links are at the top of the page across from the article title. Deep white matter hyperintensites occur deep within white matter, periventricular white matter hyperintensities occur adjacent to the lateral ventricles and subcortical hyperintensities occur in the basal ganglia. Supraspinatus Muscle and Rotator Cuff Tendonitis Treatment. A mri was taken and the impression says abnormal t2 prolongation identified in the periventricular white matter region, what does this mean? I have a had a kidney cyst since 2009. Young IR, Szeverenyi NM, Du J, Bydder GM. Functional cookies help to perform certain functionalities like sharing the content of the website on social media platforms, collect feedbacks, and other third-party features. The volume and frequency is strongly associated with increasing age. Spinal Cord Ser Cases. it also found the following: there is a focus of uniform t2 prolongation in the medial lower pole of the right kidney measuring 20 mm in diameter. These small regions of high intensity are observed on T2 weighted MRI images (typically created using 3D FLAIR) within cerebral white matter (white matter lesions, white matter hyperintensities or WMH)[1][2] or subcortical gray matter (gray matter hyperintensities or GMH). T2 weighting tends to require long TE and TR times. QT prolongation is the medical term for an extended interval between the heart contracting and relaxing. 4 How to detect T2 prolongation in skeletal muscle? Cervical (neck) spinal cord T2/FLAIR lesions could cause tingling and numbness in the hands and legs. 1. 1 doctor answer 1 doctor weighed in Share Dr. John cuong Doananswered Family Medicine 18 years experience You may have: rotator cufftendinitis, whether acute or chronic it will be hard for MRIto detect. We report the radiologic-histopathologic concordance between T2/FLAIR WMHs and neuropathologically confirmed demyelination in the periventricular, perivascular . The meaning of PROLONGED is continuing for a notably long time : extended in duration. This cookie is set by GDPR Cookie Consent plugin. There is mild heterogeneous t2 signal change within the supraspinatus and subscapularis.what does that mean? Kinesiology Tape (KT Tape) or Shoulder Sling. For example, deep white matter hyperintensites are 2.5 to 3 times more likely to occur in bipolar disorder and major depressive disorder than control subjects. T2/FLAIR images show the total amount of scar from MS from its onset. This site needs JavaScript to work properly. Video chat with a U.S. board-certified doctor 24/7 in less than one minute for common issues such as: colds and coughs, stomach symptoms, bladder infections, rashes, and more. A hyperintensity or T2 hyperintensity is an area of high intensity on types of magnetic resonance imaging (MRI) scans of the brain of a human or of another mammal that reflect lesions produced largely by demyelination and axonal loss. What does it mean when a MRI (brain) says there are ten small t2 hyperintense foci within the periventricular deep white matter. . [6], Postmortem studies combined with MRI suggest that hyperintensities are dilated perivascular spaces, or demyelination caused by reduced local blood flow. Advertisement cookies are used to provide visitors with relevant ads and marketing campaigns. Necessary cookies are absolutely essential for the website to function properly. We use cookies on our website to give you the most relevant experience by remembering your preferences and repeat visits. You also have the option to opt-out of these cookies. My dad has metastic nsc lung cancer. To understand this "paradox", you must realize that apixel's "brightness" or "darkness" on an MR image is directly related to the magnitude of the detected MR signal. Usually this is due to an increased water content of the tissue. after an RF excitation pulse, there is relaxation of the spins from the transverse plane toward the main longitudinal magnetic vector (B 0) - this is T1 weighting. "Nonspecific" usually means cause unclear/many possible causes and often implies "low concern". Gradient Diffusion Spin Echo Sequencethat is both positively T2-weighted and negatively D*-weighted. Characterization of the abnormal areas of T2 signal as well as their appearance on other MR imaging sequences, when combined with clinical context and laboratory investigations, will often allow a unique diagnosis, or at least aid in narrowing the differential diagnosis. Connect with a U.S. board-certified doctor by text or video anytime, anywhere. [12], It is also thought that WMH have a negative impact on cognition in people with Alzheimer's disease. prolongation definition: 1. the act of making something last a longer time: 2. the act of making something last a longer. My brain MRI shows "scattered areas T2 prolongation in the periventricular and subcortical white matter, a dominant left-sided lesion in left parietal white matter approx. Accessibility Background White matter hyperintensities (WMH) lesions on T2/FLAIR brain MRI are frequently seen in healthy elderly people. The above discussion presumes we are dealing with a "standard" magnitude-reconstructed spin-echo image. Dr. Stuart Hickersonanswered Family Medicine 33 years experience Talk now MRI: Your brain has ventricles which are fluid filled cavities on the inside of you brain. By using this Site you agree to the following, By using this Site you agree to the following, The Best IOL for 2022 RXSight Light Adjusted Lens, Will refractive surgery such as LASIK keep me out of glasses all my life, what is scattered signal hyperintensities in the deep left frontal white matter, T2 Hyperintense signal in the distal sacrm. Video chat with a U.S. board-certified doctor 24/7 in less than one minute for common issues such as: colds and coughs, stomach symptoms, bladder infections, rashes, and more. An estimated 25 percent of people 40 years of age and 50 percent of people 50 years of age have simple kidney cysts. You have brain structures that show up white on MRI in this area. i do not have migraines, h bp or diabetes. We disclaim all responsibility for the professional qualifications and licensing of, and services provided by, any physician or other health providers posting on or otherwise referred to on this Site and/or any Third Party Site. Without going into the physics of MRI (which I doubt even the most ardent Radiologist could explain), prolongation of the T2 signal (a bright area on , MS, normal and other. Get prescriptions or refills through a video chat, if the doctor feels the prescriptions are medically appropriate. i am only 44, what could this be? This is seen in particular on gradient echo images. 2 How do you treat inflammation of the supraspinatus tendon? This cookie is set by GDPR Cookie Consent plugin. neurologist isn't worried. A 79-year-old male asked about a 79-year-old male: Connect with a U.S. board-certified doctor by text or video anytime, anywhere. A wide range of instructive cases is discussed here, with review of the published reports focusing on pertinent MR features to aid in diagnosis. Your brain has ventricles which are fluid filled cavities on the inside of you brain. prolonged illness. We also use third-party cookies that help us analyze and understand how you use this website. The cookie is set by GDPR cookie consent to record the user consent for the cookies in the category "Functional". I am a thirty two year old femalesix feet tall and three hundred forty pounds. ? Loss of signal and darkness on T2-weighted images in cortical bone, teeth, calculi is primarily a result of little water (low proton density) unlike tendons and ligaments 3. PMC ? HealthTap uses cookies to enhance your site experience and for analytics and advertising purposes. Can a person have such a finding and still be normal? 1 What is increased T2 signal on MRI report? Quant Imaging Med Surg 2020; 10:2030-2065. This condition can increase a person's risk of experiencing abnormal heart rhythms and . The same conclusions and observations would not necessarily apply in other situations, such as if the sequence were a phase-sensitive inversion recovery one, for example. The site is secure. T2 images are a map of proton energy within fatty AND water-based tissues of the body Fatty tissue is distinguished from water-based tissue by comparing with the T1 images - anything that is bright on the T2 images but dark on the T1 images is fluid-based tissue Natural history of the cervical high-intensity intramedullary lesion in achondroplasia. Mri brain was done it showed scattered white matter foci of increased t2 prolongation. In solutions of macromolecules and tissues the relaxation rate is much faster, i.e., the T2 time is shorter. Other uncategorized cookies are those that are being analyzed and have not been classified into a category as yet. This website uses cookies to improve your experience while you navigate through the website. The resulting short T2 time causes tendons and other semi-solid tissues to appear dark on T2-weighted images. Get answers from Diagnostic Radiologists and top U.S. doctors, Our doctors evaluate, diagnose, prescribe, order lab tests, and recommend follow-up care. RE: differential diagnosis of T2 hyperintense spinal cord lesions. Speed of cognitive processes and frontal skills may also be impaired in people with WMH. (1999) ISBN:0815185189. Please note, we cannot prescribe controlled substances, diet pills, antipsychotics, or other commonly abused medications. The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. I was advised a T2 hyperintense structure on my left kidney was found on an MRI I had for back problems. Please note, we cannot prescribe controlled substances, diet pills, antipsychotics, or other abusable medications. The cookies is used to store the user consent for the cookies in the category "Necessary". My Dad has metastic NSC Lung cancer. How to detect T2 prolongation in skeletal muscle? and now this .What is going on with me? The cookie is used to store the user consent for the cookies in the category "Other. Note: T2 relaxation is not to be confused with T2*, which is a broader phenomenon and includes static magnetic field effects in addition to the tissue-characteristic T2 relaxation. What does this mean? Learn more. To learn more, please visit our, Your brain has ventricles which are fluid filled cavities on the inside of you brain. That is the case with my hubby. {"url":"/signup-modal-props.json?lang=us"}, Bashir U, Rock P, Murphy A, et al. This is related in part to the slower motion of protons both in macromolecules as well as water molecules attracted to the surface of the macromolecule. I received my MRI result today. The water that is in bone, teeth, and calculi would mostly be bound as to collagen and would have a very short T2 time constant and appear dark. For example, a brainstem lesion can cause room spinning sensations and balance problems. Subacute combined degeneration of the spinal cord (SCD). An abnormal prolongation can be associated with metabolic problem 3.8k views Reviewed >2 years ago Thank Dr. Melissa Gowans and another doctor agree 2 thanks Last updated Jul 13, 2018 Found in: Educational text answers on HealthTap are not intended for individual diagnosis, treatment or prescription. A T2WI relies upon the transverse relaxation (also known as "spin-spin" relaxation) of the net magnetization vector (NMV). However, when T2 and D* are both decreased as with many prostate tumors, the T2 contrast is negative and the D* contrast is positive. Sufficient damage to the axons that course through WMH can cause adequate interference with normal neuronal functions. [9] Severe WMH is consistently shown to be associated with gait disorders, impaired balance and cognitive disturbances. Except for some minimal right periventricular white matter T2 brightness which is overall nonspecific and minimal is otherwise . Senol MG, Sonmez G, Ozdag F, Saracoglu M. Do-Dai DD, Brooks MK, Goldkamp A, Erbay S, Bhadelia RA. The result is that the Mxy component of the magnetic vector decreases exponentially as a function of the T2 time constant (Figure 1). What does Mild periventricular and subcortical abnormal T2 andsparing posterior fossa and brainstem mean on mri? These cookies will be stored in your browser only with your consent. For potential or actual medical emergencies, immediately call 911 or your local emergency service. Tuberculous Myelopathy Associated with Longitudinally Extensive Lesion: A Clinicoradiological Review of Reported Cases. Stark DD, Bradley WG, Bradley WG. V1/T1 = V2/T2 Where temperature must be in Kelvins 67C + 273 = 340 K So 140/340 = 50/T2 Find T2 340/140 (50) = T2 T2 = 121 K or -152C. A short T2 means that the signal decays very rapidly. What causes increased signal in the normal supraspinatus tendon? It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. This cookie is set by GDPR Cookie Consent plugin. 11, 23 It is still unclear the number of cases in which these causes of T2-signal increase may . It is difficult to answer your question with this isolated finding. Whether these radiological lesions correspond to irreversible histological changes is still a matter of debate. While the overall length of stay in the hospital was similar between patients with and without an increase in the T2 signal intensity (12.5 vs 10.3 days, respectively, p = 0.22), patients with an increased T2 signal intensity spent significantly more time in the ICU, and there was a strong trend toward an increased length of dependence on . How do you treat inflammation of the supraspinatus tendon? Advanced Discussion (show/hide) References Elster AD. White matter disease is an umbrella term for damage to your brain's white matter caused by reduced blood flow to the tissue. The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. Unable to load your collection due to an error, Unable to load your delegates due to an error. Each magnetic dipole exists in a microenvironment unique to the tissue where it belongs. T2 relaxation. i noticed on my mri results that it said there is a single punctate focus of t2 prolongation in the left corona radiata, nonspecific. Farr's physics for medical imaging. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. Do you have any symptoms now? after an RF excitation pulse, there is relaxation of the spins from the transverse plane toward the main longitudinal magnetic vector (B 0) - this is T1 weighting. You have 4 two lateral venticles, and two midline. Alteration in muscle T2, notably T2 prolongation due to increased intracellular or extracellular free water (muscle edema), is best detected with inversion-recovery and fat-suppressed T2-weighted images (, 1,, 2 ). Many similar examples of additive (augmenting) or subtractive (competing) image contrasts between two tissue components may be cited. A mri was taken and the impression says abnormal t2 prolongation identified in the periventricular white matter region, what does this mean? Check for errors and try again. Supraspinatus tendinopathy can be graded using a modified 4-point scale from 0 to 3 based on previous studies. [3][4] WMH volume, calculated as a potential diagnostic measure, has been shown to correlate to certain cognitive factors. I recently had an MRI to rule out a pseudotumor cerebri. How to use prolonged in a sentence. For example, a brainstem lesion can cause room spinning sensations and balance problems. Epub 2015 Jul 14. Bookshelf Neurol Sci. Particular features of the focal lesions on MR images (number, size, location, presence or lack of edema, reaction to contrast medium, evolution in time), as well as accompanyi Get prescriptions or refills through a video chat, if the doctor feels the prescriptions are medically appropriate. So substances with short T2's have smaller signals and appear darker than substances with longer T2 values. Long T2 fluids with few macromolecules such as water, urine, and CSF will appear bright on T2-weighted images. A: When making the diagnosis of MS, brain and cervical spinal cord MRIs should be obtained in all cases unless specific contraindications. Federal government websites often end in .gov or .mil. 1.6 x 0.7 cm and a dominant right-sided lesion in the parietal white matter approx. Background: White matter hyperintensities (WMH) lesions on T2/FLAIR brain MRI are frequently seen in healthy elderly people. The biophysical basis of tissue contrast in extracranial MR imaging. Performance cookies are used to understand and analyze the key performance indexes of the website which helps in delivering a better user experience for the visitors. What does "increased T2 prolongation involving the right midbrain" mean on his MRI? "Nonspecific white matter changes". What is thought to influence the overproduction and pruning of synapses in the brain quizlet? ), An index system for comparative parameter weighting in MR imaging, New options for increasing the sensitivity, specificity and scope of synergistic contrast magnetic resonance imaging (scMRI) using Multiplied, Added, Subtracted and/or FiTted (MASTIR) pulse sequences, Pulse sequences as tissue property filters (TP-filters): a way of understanding the signal, contrast and weighting of magnetic resonance images. [2] They are also seen in a number of neurological disorders and psychiatric illnesses. Before Generally, the lesions remain bright for only 1-2 months. a focus of T2 hyperINTENSITY means that the signal from that area has different tissue characteristics compared to normal brian tissue. i have been morbidly obese most of my life recently losing over a hundred pounds but still no improvement. Analytical cookies are used to understand how visitors interact with the website. T2 reflects the length of time it takes for the MR signal to decay in the transverse plane. To the right are images of a brain tumor with intrinsically long T1 and T2 values having opposite intensities on T1- and T2-weighted images. One that immediately comes to mind (suggested by my colleague Graeme Bydder) is the Pulsed I had a lumbar mri due to increased pain and found a lot of degenerative changes. - Radiology Community. Almost immediately, they lose coherence as some spin slightly faster than the others. Does a "focus of T2 hypersensitivity" on an MRI always mean a lesion, or can it mean something else? Also how common are such findings that are "nonspecific"? In an MRI report, the white spots might be described as: "High signal intensity areas". MRI found mild scattered foci of abnormal T2 signal are demonstrated in peri ventricular white matter, particularly along frontal convexities. Imaging of the spine in multiple sclerosis. The pictures show both old and new inflammation. Whether these radiological lesions correspond to irreversible histological changes is still a matter of debate. MedHelp is not a medical or healthcare provider and your use of this Site does not create a doctor / patient relationship. 2010 Jul-Aug;39(4):160-85. doi: 10.1067/j.cpradiol.2009.05.004. [citation needed], Hyperintensities are often seen in auto immune diseases that have effects on the brain. [5] Hyperintensities appear as "bright signals" (bright areas) on an MRI image and the term "bright signal" is occasionally used as a synonym for a hyperintensity. Mri report.multiple nonspecific small subcortical foci of t2 prolongation in the left cerebrum. 3. What is the grading scale for supraspinatus tendinopathy? By clicking Accept All, you consent to the use of ALL the cookies. T2/FLAIR lesions can directly account for some symptoms. I have been hospitalized 3 times with rhabdo with a CPK of 7715. Unauthorized use of these marks is strictly prohibited. . The poor blood supply and vascularity of tendons mean that is can take a long time for them to heal on there own. How long does supraspinatus tendinopathy take to heal? 2021 May 27;7(1):46. doi: 10.1038/s41394-021-00411-8. In pure water T2 is long, about 3-4 seconds because water molecules move considerably faster than the Larmor frequency. It says multiple (greater than 25) small abnormal T2/flair signal throughout the periventricular deep and subcortical whitemat? For these, please consult a doctor (virtually or in person). Simple kidney cysts are more common as people age. We offer this Site AS IS and without any warranties. to serve as a baseline evaluation and staging the disease process. 2008 Dec;52(6):535-43. doi: 10.1111/j.1440-1673.2008.02017.x. thanks. Doctors typically provide answers within 24 hours. However, you may visit "Cookie Settings" to provide a controlled consent. A mri was taken and the impression says abnormal t2 prolongation identified in the periventricular white matter region, what does this mean? Call your doctor or 911 if you think you may have a medical emergency. Many of the lesions may not be causing obvious symptoms. Would you kindly let me know what this means. Saunders Ltd. (2007) ISBN:0702028444. Who wrote the music and lyrics for Kinky Boots? By using our website, you consent to our use of cookies. The prevailing view is that these intensities are a marker of small-vessel vascular disease and in clinical practice, are . Differential diagnosis of T2 hyperintense spinal cord lesions: Part A. National Library of Medicine J Med Imaging Radiat Oncol. "The clinical importance of white matter hyperintensities on brain magnetic resonance imaging: systematic review and meta-analysis", "White matter hyperintensities and imaging patterns of brain ageing in the general population", "Meta-analysis, Database, and Meta-regression of 98 Structural Imaging Studies in Bipolar Disorder", "Testing the white matter retrogenesis hypothesis of cognitive aging", "Volume of white matter hyperintensities in healthy adults: contribution of age, vascular risk factors, and inflammation-related genetic variants", Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, "Medial temporal lobe atrophy and white matter hyperintensities are associated with mild cognitive deficits in non-disabled elderly people: The LADIS study", "Regional white matter hyperintensities: aging, Alzheimer's disease risk, and cognitive function", "A New Visual Rating Scale to Assess Strategic White Matter Hyperintensities Within Cholinergic Pathways in Dementia", https://en.wikipedia.org/w/index.php?title=Hyperintensity&oldid=1140382689, Short description is different from Wikidata, Articles with unsourced statements from November 2012, Creative Commons Attribution-ShareAlike License 3.0, This page was last edited on 19 February 2023, at 21:27.